Question paper- IIT-JAM 2008

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IIT-JAM questions paper 2006

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IIT Question Paper - Biotechnology 2005

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Sample Questions - PART 13

Q) Capping occurs when

1. The trascription is complete
2. The trascritption changes from initiation to elongation phase
3. The elongation phase is complete
4. When RNA is in cytoplasm
5. None of the above

Q) The component that act as a DNA mimic in prokaryotic RNA polymerase is

1. Beta component
2. Alpha component
3. Sigma 3.2
4. Sigma 1.1
5. None of the above

Q) Which of the following is not a DNA intercalating agent

1. Ethidium Bromide
2. oxoG
3. Proflavin
4. Acridines
5. Exo 8,9 epoxide of aflatoxin B1

Q) Huntington's disease is a type of
1. Trinucleotide repeat disorder
2. Autosomal recessive disorder
3. Non-Autosomal recessive disorder
4. Non-Autosomal dominant disorder
5. Cardiac disorder

Q) The eukaryotic DNA polymerase respondible for replicating the ribosomal DNA is
1. Pol alpha
2. Pol beta
3. Pol epsilon
4. Pol gamma
5. Pol Delta

Q) The amino acids that are rarely found in alpha helix are
1. Proline and methionine
2. Proline and valine
3. Proline and serine
4. Proline and histidine
5. Alanine and proline

Q) SOS response in prokaryotes repair the DNA damage using
1, Base excision repair
2. Non homologous end joining
3. Mismatch repair
4. Trasletion DNA synthesis
5. Doublestrand break repair

Q) End problem is not seen in
1. Leading strand
2. Lagging strand
3. Linear DNA
4. Circular DNA

Q) Topoisomerases help in
1. Decatenation and catenation
2. Base excision repair
3. Reduce negative supercoiling
4. Recombinational repair
5. Non-homologous end joining

Q) The defect is on a gene that codes DNA helicase causes
1. Werner syndrome
2. Bloom's syndrome
3. Ataxia telangiectasia
4. Hay-Wells syndrome
5. Fibromyalgia

Sample Questions - PART 12

Q) Which of the following statement(s) is/are true

1. There is no movement of water across isoosmotic solutions

2. Stenohalines includes only osmoconformers

3. Euryhalines can tolerate large osmotic changes in the environment

4. Water moves from a hyperosmotic solution to hypoosmotic solution

5. Both 3 and 4


Q) The only statement true among the following is

1. Fresh water fishes include only osmoregulators

2. Marine water fishes have a problem of gaining large quantities of water

3. Marine water fishes are hypertonic to seawater

4. Fresh water fishes are hypotonic to their surrounding water

5. None of the above


Q) The human urine is

1. Hypoosmotic compared to interstitial fluids

2. Hyperosmotic compared to interstitial fluids

3. Isoosmootic compared to interstitial fluids

4. Made hypoosmotic in cortical nephrons

5. Made hyperosmotic in cortical nephrons


Q) The decending limb loop of Henle

1. Has many aquaporins

2. Is permeable to salts

3. Is impermeable to water

4. Makes urine dilute

5. None of the above



Q) The part in human body impermeable to water is

1. Decending limb of loop of Henle

2. Ascending limb of loop of Henle

3. Glomerulus

4. Bowman's capsule

5. All the above


Q) During an allergic response, Histamin is released from

1.B Lymphocytes

2. T lymphocytes

3. Mast cells

4. Special lymphocyte that also secret IgE


Q) Prostaglandins are biologically active molecules that are
1. monocyclic

2. Bicyclic

3. Tricyclic

4. Polycyclic
5. None of the above

Sample Questions - PART 11

Q) At the organismal level Tay-Sach syndome is due to




1. Incomplete dominance

2. Codominance

3. Homozygous recessive allele

4. Homozygous dominant allele

5. Heterozygous recessive allele




Q) The ozygen binder in Hemocyanine is




1. Magnesium

2. Copper

3. Cobalt

4. Iron

5. Zinc




Q) What change in the dissociation curve of hemoglobin is produced when there is a decrease in pH in tissues




1. Curve shifts to right side

2. Curve shifts to left side

3. Line parallel to X- axis

4. Line parallel to Y-axis

5. None of the above




Q) There is a production of H+ inside the erythrocytes when the CO2 enters the erythrocyte




H2CO3 = HCO3- + H+




. The Bohr shift is not occuring in RBC as a result of this because




1. H+ is removed back to tissues

2. H+ is taken by hemoglobin

3. H+ is converted to H2O

4. H+ is liberated as Hydrogen gas

5. None of the above




Q) In humans most of the carbon dioxide produced is trasported to lungs as




1. CO2 dissolved in blood

2. CO2 attached to amino end of polypeptide chain of hemoglobin

3. HCO3- in plasma

4. H2CO3 in erythrocytes

5. None of the above




Q) Rate of oxgen consumption per gram of body mass of a mouse and an elephant suggests that




1. As animals increase in size the rate of consumption of oxygen per gram of body mass increases

2. As animals increase in size the rate of consumption of oxygen per gram of body mass decreases

3. Whatever be the size of animal the rate of consumption of oxygen per gram of body mass remains constant

4. None of the above




Q) The mouse color genes exhibits




1. Pleitropy

2. Epistasis

3. Codominance

4.Semidominace

5. None of the above

Sample Questions - PART 10

Q) Which is true about arteries

1. They carry oxygen containing blood

2. They carry deoxygenated blood

3. They carry blood towards capillaries

4. They carry blood away from capillaries

5. Both 1 and 4

Q) Which of the following is not seen in serum

1. Immunoglobulins

2. Protein

3. Clotting factors

4. Plasma

5. None of the above

Q) The best description of Acclimatization is

1. It is an irreversible change

2. It is similar to adaptation

3. It is a temporary change

4. It contributes to natural selection more than any otjer factor

5. None of the above

Q) As the stroke volume increases the heart rate

1. Increases

2. Decreases

3. Remains the same

4. Increases first then decreases

5. None of the above

Q) Mitochondria is not seen in RBC. This means that

1. RBCs are dead cells

2. They depend upon anaerobic matabolism

3. They donot produce ATP

4. They are attracted more towards ozygen

5. Both 3 and 4

Q) Arthrosclerosis is caused due to the clot in the arteries. This clot is due to

1. HDL

2. Clptting factors in blood

3. LDL

4. Low blood pressure

5. High blood pressure

Q) When the pH of the CSF decreases, the breathing rate

1. Increases

2. Decreases

3. This has no effect

4. Stops

4. None of the above

Q) With increase in age

1. The tidal volume increases

2. The vital capacity increases

3. The residual volume decreases

4. The tidal volume decreases

5. The residual volume increases

Q) The respiration in humans can be considered as

1. Positive pressure ventilation

2. Negative pressure ventilation

3. Both 1 and 2

4. None of the above

5. Positive durinf inhalation and nagative during exhalation